Ranpirnase - New HPV Treatment

A new and potential antiviral, ranpirnase, has been proven in trial to get rid of the dreaded genital warts. So far, the only successful treatments for this cursed infection get rid of the warts initially but cannot guarantee their return. However, ranpirnase will target the virus directly. Research is currently being carried out at Tamir Biotechnology with the use of cultured human and rabbit cells.


The drugs works by attacking RNA (Ribonucleic acid cells), and thus stops the virus replicating. It is administered in the form of a lotion to the skin and penetrates beyond the top layer of skin into the dermis. 13 human patients administered the lotion twice daily and were seen observed over a period of eight weeks.


Excitingly, half way through the trial, it was found that 30.8% of patients had zero warts. Approximately 46% got rid of half their warts. All of the participants experienced an improvement. By the end of the eight week period, none of the patients had any warts.


Trials will continue and next on the list will be the gleaning of the viral load of the infected cells as the weeks pass. Recurrence rates will also be a primary focus and so a longer term trial will be put in place.


Considering the drug works directly on the virus, it could only be good news for other types of HPV that cause HPV related cancers instead. This ever increasing form of cancer is a real worry however, if caught on time, is the easiest form of cancer to cure. Results like these offer hope.


Genital warts are difficult to clear as the immune system really needs to be working at its optimum to fight them. Whenever there is a dip in the immune system they are likely to return where they have previously been cleared. For some people, genital warts is a lifelong battle of outbreaks, an embarrassing problem that can impact seriously on someones confidence and their intimate life. This treatment and others like it might be the end of warts, maybe even the end of HPV.  


You can read more about Ranpirnase here.